According to the National Institute on Drug Abuse, close to half of young people surveyed in three recent studies who have injected heroin said they had abused prescription painkillers before they started using heroin.
How does heroin effect the brain?
When someone injects, snorts, or smokes heroin, the brain converts it into morphine. Morphine binds to molecules on cells located throughout the brain and body called opioid receptors, which affect how we perceive pain and rewards.
This explains the surging sense of euphoria that many people feel when they inject the drug straight into the bloodstream. After the initial "rush," the skin gets flushed and warm, the arms and legs start to feel heavy, and thinking slows.
Because we also have opioid receptors in our brain stem — the body's main control center that is in charge of automatic processes such as blood pressure and breathing — overdosing on heroin can slow and even stop breathing, leading to brain damage or coma.
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